Oser Lab - New Targeted Approaches for Small Cell Lung Cancer
Welcome to Oser Lab!
Laboratory Overview: The Oser laboratory uses CRISPR/Cas9 functional genomics to uncover vulnerabilities in small cell lung cancer (SCLC) related to tumor suppressor genes, undruggable transcription factors, and neuroendocrine differentiation. We then study how inactivation of these novel targets impacts SCLC tumorigenesis in a CRISPR-based genetically-engineered mouse model of SCLC.
Mission: We seek to elucidate new mechanisms that are required for SCLC tumorigenesis. Our ultimate goal is to make discoveries that will lay the foundation for the development of new targeted therapies for SCLC. We are also deeply committed to mentoring highly motivated physicians and scientists.